Currently, neotame has been approved by more than 100 countries for use in more than 1000 kinds of products.
It is suitable for use in carbonated soft drinks, yogurts, cakes, drink powders, bubble gums among other foods. It can be used as a table top sweetener for hot drinks like coffee. It covers bitter tastes .
HuaSweet neotame complies with the Chinese national standard GB29944 and strictly meets the FCCVIII, USP, JECFA and EP specifications. HuaSweet has established sales network in over eighty countries throughout Southeast Asia, Europe, South America, North America and Africa.
In 2002, FDA approved it as a non-nutritive sweetener and flavor enhancer within United States in foods generally, except meat and poultry.[3] In 2010, it was approved for use in foods within EU with the E number E961.[5] It has also been approved as an additive in many other countries outside US and EU.
In US and EU, the acceptable daily intake (ADI) of neotame for humans is 0.3 and 2 mg per kg of bodyweight (mg/kg bw), respectively. NOAEL for humans is 200 mg/kg bw per day within EU.
Estimated possible daily intakes from foods are well below ADI-levels. Ingested neotame can form phenylalanine, but in normal use of neotame, this is not significant to those with phenylketonuria. It also has no adverse effects in type 2 diabetics. It is not considered to be carcinogenic or mutagenic.
The Center for Science in the Public Interest ranks neotame as safe.